Get Everything Done

This is very much a question of personal preference. For people who work in a different location from home I recommend a separate Will Do list for each location. The content of each Will Do list is not based on whether it's work or personal, but where it needs to be done. So you might have some personal items which you need to do in the office (such as call the bank, lunchtime shopping, etc.) so they go on the Office Will Do list.

If you're working at home, it's more difficult to make this separation between the two lists. One way of doing it would be by time. If, as you say, you have a set structure of work and personal time, then you can divide tasks according to whether you intend to do them in the work hours or not. So a task like calling the bank re your persoanl account could fall into the work period, even though it's a personal task.